Confederate defenders abandon a position on the Mississippi River under artillery bombardment from John Pope’s Army of the Mississippi.
Federal forces push Sterling Price’s Missouri State Guards out of their home state, where they join a new army and prepare to counterattack.
Henry W. Halleck issues General Orders as part of his Federal program to suppress alleged disloyalty in Missouri.
Federals under John Pope overwhelm a force of Missouri State Guards and demoralize secessionists in the western part of the state.
Sterling Price sends another message to Jefferson Davis asking him to provide more support for their secessionist cause in Missouri.
Ulysses S. Grant’s Federal army narrowly escapes destruction in southwestern Missouri but gains important battle experience.