William S. Harney is ousted as Federal commander in Missouri, leaving his successor free reign to make war on secessionists in the state.
A riot breaks out in St. Louis as Federal forces struggle to maintain order and Missourians flee their state.
Nathaniel Lyon and his Federal Home Guard cause controversy in Missouri by forcing the surrender of an allegedly pro-Confederate state militia force.
The governor of Missouri asks Jefferson Davis to send him arms while Federals work in secret to secure the vital St. Louis arsenal.
The states of the upper South and the border with the North continue to contemplate joining the Deep South in seceding.