Confederate defenders abandon a position on the Mississippi River under artillery bombardment from John Pope’s Army of the Mississippi.
Federals under John Pope overwhelm a force of Missouri State Guards and demoralize secessionists in the western part of the state.
John C. Fremont leaves St. Louis to lead his Army of the Southwest against the secessionist Missouri State Guards of Sterling Price.
John C. Fremont issues controversial orders imposing martial law throughout Missouri and authorizing the forced emancipation of slaves.
Political turmoil and military maneuvering continue in the bitterly divided state of Missouri.
Federal commanders accepted the surrender of the last major organized Confederate force still in the field.