The Lincoln administration approves centralizing efforts to aid volunteer soldiers into a unified U.S. Sanitary Commission.
A conference between Federal officers and Missouri state officials leads to open warfare between the Federals and Missourians.
Federal forces win a minor victory in western Virginia and secure the railroad line between Washington and the West.
The first land battle of the war takes place in northern Virginia, and Confederates blockade the Potomac waterway into Chesapeake Bay.
William S. Harney is ousted as Federal commander in Missouri, leaving his successor free reign to make war on secessionists in the state.
Benjamin F. Butler causes another controversy, this time by refusing to return fugitive slaves to their masters. This sets a wartime precedent.